Peyronie's Disease


International Andrology Treatment Protocol

Our Peyronie’s disease treatment procedure is based on the latest medical research, medical guidelines and our extensive clinical experience and with our treatment options, you may be able to avoid surgery.

In the past (and still the treatment plan that most doctors follow), newly diagnosed patients with acute phase of Peyronie’s, were limited to conservative treatment options with minimum or no effect on the Peyronie’s plaque and curvature. Patients only option was to wait until the disease progressed to the chronic phase (around 12 months from onset) and then consider surgical correction.

Since the introduction of Xiapex 2 years ago and based on the latest research, we have revised our treatment plans, introducing a first stage and second stage of treatment as outlined below.

First line of treatment

Irrespective of whether a patient is in the acute or chronic phase of the disease, we now recommend the following procedure as a first step in a treatment plan:

  • Oral intake of Pentoxifylline 400mg tablets twice a day +

  • Cialis 5mg daily for patients with some degree of erectile dysfunction +

  • A course of Xiapex injections +

  • Mechanical modelling

Patients that suffer from very severe erectile dysfunction, complete plaque calcification and have ventral curvatures (downward facing) are not appropriate candidates for Xiapex injections and if they have progressed to the acute phase, then the traditional (wait until the chronic phase) method applies to them. If they are in the chronic phase then they may need to consider a surgical option.

Second line of treatment

If you are diagnosed as to be not receptive to Xiapex injections or there is residual curvature still present following the first stage of treatment AND the disease has stabilised and is in the chronic phase, then the surgical correction will need to be considered. The degree of surgical correction will be decided together with your doctor but in general, the following patient-specific criteria will need to be taken into account:

  • Severity and complexity of curvature;

  • Whether there is presence of destabilising hour-glass deformity or hinge;

  • Whether a patient has experienced significant length loss due to Peyronie’s and the degree of irritation caused by this

  • Whether you suffer from erectile dysfunction and how severe your diagnosis is

In general, our surgeon’s can perform any type of surgical correction for Peyronie’s disease and during your consultation they will help you decide which is the most appropriate technique for your specific case. Further information regarding the different techniques can be found in the following sections:

I am suffering from a what I suspect is Peyronies disease, what should I do next?

If you believe you are suffering from Peyronies and it causes you significant concern we advise you to see a specialist urologist/andrologist.

Our doctors have vast experience treating Peyronies and our clinic is an international referral centre for patients suffering from this condition. We would be happy to review your case and treat you in our clinic.